CAS NO.367514-88-3 Lurasidone hydrochloride CAS NO.367514-88-3

•                                                Description                                       

 lurasidone characteristics of atypical antipsychotic drugs, the exact mechanisms in the treatment of schizophrenia like other atypical antipsychotics as not very clear, may be related to the dopamine D2 and serotonin (5-HT2A 5- 2A) on the antagonistic effect of receptor. For the treatment of schizophrenia, studies have reported lurasidone can improve cognitive function.
Adverse reaction: common adverse reactions are nausea, somnolence, sit not, Parkinson's disease and anxiety. Lurasidone no physical dependence. Lurasidone less cause weight gain, is not caused by glucose, lipid (Lei Zhi), change ECG and QT interval.
Contraindications: any known on ATUDA or the preparation of any of the components of hypersensitivity. At the same time, giving a strong CYP3A4 inhibitors such as [ketoconazole], ketoconazole and inducers such as rifampin, [rifampin].Cerebrovascular adverse reaction: antipsychotic use in atypical with dementia related psychosis in elderly patients treated had seen the incidence of cerebrovascular adverse events (such as increase, stroke, transient ischemic attack); neuroleptic malignant syndrome: immediate termination of treatment and close monitoring; tardive dyskinesia: such as clinical appropriate withdrawal; metabolic changes: atypical antipsychotics have accompanied by metabolic changes may increase cardiovascular / CEREBROVASCULAR risk. These metabolic changes including hyperglycemia, dyslipidemia, and weight gain.
Hyperglycemia and diabetes: monitoring in patients with hyperglycemia symptoms include polyuria, polydipsia, polyphagia, and weak. In patients with diabetes or at risk of diabetes in the regular monitoring of glucose.

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Nanjing Yuansenthai Biological Technology Co.,Ltd. is a manufacturing company of research chemicals in China,which have been on the market since year 2010.

Headquartered in Nanjing, it has a group of research and development team with many years of rich experience in drug development and rich project management ability.The company has 6500 square meters of GMP standard workshop, Its technology portfolio comprises low temperature,high pressure reactions and continuous processing,Yuansenthai runs its technologies on dedicated and multipurpose equipments on all scales under a quality system based on the process ISO 9001:2015.Equipped with a variety of complete and advanced testing equipment, including LC/MS/MS, DSC, TGA, ICP/MS, GC/MS, HPLC, GC, H-NMR,at the same time, we keep close cooperation with some universities, ensure the smooth progress of pharmaceutical technology development research.

Yuansenthai’s one-site strategy allows reduced decision and communication pathways, thus ensuring rapid and efficient project development as well as clear and transparent communication with customers.We sincerely hope to establish long-term cooperation and common development with our customers.

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