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Home > Products >  Top quality raw material powder for Breast Cancer Trilostane

Top quality raw material powder for Breast Cancer Trilostane CAS NO.58-22-0

  • FOB Price: USD: 45.00-45.00 /Gram Get Latest Price
  • Min.Order: 10 Gram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
  • Available Specifications:

    99%(5-10)Gram

  • Product Details

Keywords

  • Testosterone 99%
  • Testosterone Powder
  • high quality Testosterone

Quick Details

  • ProName: Top quality raw material powder for Br...
  • CasNo: 58-22-0
  • Molecular Formula: C19H14F3N3O3
  • Appearance: white powder
  • Application: meidical grade
  • DeliveryTime: Delivery within three days after payme...
  • PackAge: aluminium foil bag
  • Port: Any port
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 99%
  • LimitNum: 10 Gram
  • Grade: Pharma Grade

Superiority

Trilostane is an inhibitor of isoforms 3β-HSD and 3β-HSD2 of the enzyme 3β-hydroxysteroid dehydrogenase, which plays a role in adrenal steroid biosynthesis. Investigators believe that Arg195 in 3-HSD versus Pro195 in 3β-HSD2 attributes to the competitive inhibition of 3β-HSD, but not 3β-HSD2 by Trilostane. Research shows that trilostane is effective in suppressing the intracellular production of dihydrotestosterone in LNCaP-FGC prostate cancer cells and inhibiting cortisol biosynthesis in the human adrenal gland. This product serves as a useful tool in steroid biosynthesis research.

Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.

Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.

Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.

Details

 

Nanjing Yuansenthai Biological Technology Co.,Ltd. is a manufacturing company of research chemicals in China,which have been on the market since year 2010.

Headquartered in Nanjing, it has a group of research and development team with many years of rich experience in drug development and rich project management ability.The company has 6500 square meters of GMP standard workshop, Its technology portfolio comprises low temperature,high pressure reactions and continuous processing,Yuansenthai runs its technologies on dedicated and multipurpose equipments on all scales under a quality system based on the process ISO 9001:2015.Equipped with a variety of complete and advanced testing equipment, including LC/MS/MS, DSC, TGA, ICP/MS, GC/MS, HPLC, GC, H-NMR,at the same time, we keep close cooperation with some universities, ensure the smooth progress of pharmaceutical technology development research.

Yuansenthai’s one-site strategy allows reduced decision and communication pathways, thus ensuring rapid and efficient project development as well as clear and transparent communication with customers.We sincerely hope to establish long-term cooperation and common development with our customers.

 

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